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PROGRESS REPORT 12
Totelle Img
Client: Wyeth
October 22, 2002
PROJECT
CLASSIFICATION
TARGET
STATUS / ACTION
SUBMISSION
DATE /JOURNAL
Paper PS(3)
Hemostasis/metabolic impact
April 2003
Metabolic and hemostatic profile of
First draft submitted for initial review April 19
postmenopausal women receiving a
Comments received from Gary May 13
combined sequential regimen of
Revised draft to be submitted December
Comments expected January 13
either 1mg estradiol and
trimegestone or estradiol and
Final paper to be submitted for review February 10
Sign-off expected March 24
norethisterone over a 1-year period
PAPERS FOR WMC SYMPOSIUM PROCEEDINGS
Paper WMC(1)
Preclinical
The preclinical biology of
December, 2002
First draft submitted for initial review July 29
trimegestone: a new potent and
Climacteric Suppl
selective progestin
R. Winneker
Paper WMC(2)
Safety
An overview of the comparative
Bleeding profile
December, 2002
First draft submitted for initial review August 1
efficacy, safety, bleeding profile and
Metabolism
Climacteric Suppl
Comments received from Gary October 9
Revised draft to be submitted Oct 31
effect on lipids of a sequential HRT
preparation containing 2 mg
estradiol and trimegestone
H.P.G. Schneider
Paper WMC(3)
Bone
A comparative clinical evaluation of
December, 2002
First draft submitted for initial review July 30
the effect of a new sequential HRT
Climacteric Suppl
Comments received from Gary October 14
Revised draft to be submitted Oct 31
preparation containing 2 mg
estradiol and the progestin
trimegestone on postmenopausal
bone loss
M. Gambacciani
Paper WMC(4)
A comparative clinical evaluation of
Climacteric symptoms
Efficacy
December, 2002
First draft submitted for initial review August 9
Comments received from Daniele October 9
a continuous HRT preparation
Climacteric Suppl
Revised draft to be submitted October 25
containing 1 mg estradiol and the
Comments expected November 1 1
novel progestin trimegestone
P. Bouchard
PAPERS FOR PROGESTIN SYMPOSIUM
Clinical experience with
2" International
trimegestone as a new progestin in
Paper prepared and in review
Progestin
HRT
Symposium
Sienna
G. Grubb
SUPPORTING ACTIVITIES
N
Confidential Pursuant to Confidentiality
OLIVS021-014870
Order
Source: https://www.industrydocuments.ucsf.edu/docs/xqvw0217

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